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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by jfm1330on Mar 08, 2022 9:37pm
173 Views
Post# 34497914

RE:RE:RE:RE:RE:RE:RE:Pre-Clinical only!

RE:RE:RE:RE:RE:RE:RE:Pre-Clinical only!I read the three abstracts. They pushed the scope of what was already established by using human cancer stem cells in xenograft model on nude mice. Nude mice are mice without a fonctionnal immune system. They also tested TH1902 on mice with a fonctional immune system, by grafting (allograft) them murine cancer cells (mice cancer cells). They saw that docetaxel alone was more efficacious on those murine cancer cells, but TH1902 even more. So they just expanded the scope of experiments on animal models. That is all well, but obviously, we are interested by the proof of concept on humans. The big question remains.
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