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biOasis Technologies Ord Shs V.BTI.H

Alternate Symbol(s):  BIOAF

Bioasis Technologies Inc. is a Canada-based biopharmaceutical company focused on research and development of technologies and products intended for the treatment of patients with nervous system, including central nervous system, diseases and disorders. The Company is engaged in the development of its xB 3 platform, which is a peptide-based technology, for the transport of therapeutic agents, in particular biological products, across the blood-brain barrier (BBB). It is focused on both orphan drug indications, including brain cancers, and rare genetic neurodegenerative diseases and neuroinflammatory conditions. The Company is also focused on its Epidermal Growth Factor (EGF) platform for treating rare and orphan neurodegenerative and neuroinflammatory disorders. EGF is a protein that stimulates cell growth and differentiation, notably for myelin producing cells. Its development programs include xB3-001: Brain Metastases, xB3-002: Glioblastoma and xB3-007: Neurodegenerative Disease.


TSXV:BTI.H - Post by User

Comment by JDavenporton Apr 23, 2022 12:10pm
170 Views
Post# 34626246

RE:XB3 and its cost in the health care system?

RE:XB3 and its cost in the health care system?
My understanding, narmac, is that the manufacturing of a drug like xB3-001 using a genetically programmed cell line to produce fusion proteins, is not that much different than producing the Herceptin monoclonal antibody (mAb) without xB3. In a fusion protein, the xB3-Payload combination are produced in a unit by the cell line and that's why they're called fusion proteins
 
It's probably a long shot speculation but it would be interesting if Protalix is working on producing xB3-001 using their ProCellEx technology. Using plant cells to manufacture mAbs is considerably less expensive than using the tightly-controlled environments and sophisticated equipment of using mammalian cell lines as WuXi does.
 
And then there is the commercial return of drugs like xB3-001 that can mitigate all costs of production. Big money...
 
jd
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