RE:BTD timeline...I believe that 67% or better was for AA not for BTD. But later they changed it to "significant efficacy " as potential for AA. BTD could be applied for at any time we have 60% CR on evaluable Optimized patients and 18% PR with a potential of up to 83% so far. Numbers can go up or down 10-15% at this time point depending on outcome of next 25 patients. IMO. Of course for AA we would need a significant amount of those patients to remain CR at 12-15 months. We shall hopefully see this in next few months .