RE:RE:PMN-267AZ, disagree with you. Not the same old PR's. I assume you read the press release and understand it. I don't recall Promis devoting a PR solely to ALS. You diminish and minimize the press release with a large amount of significant content and considerable "milestones". I hope Promis has the answer to this horrible disabling desease. A good friend of mine, a Psychiatrist, came to a Christmas party and sat next to me. He was using his left hand on his phone at age 41. He told me he was having issues with his right hand. He had four children under the age of 8. Two years later he was completely immobile, bedridden and had a tracheotomy-ALS. I am hoping and betting that Promis has the answer, nobody else is close on this disease as far as I know.