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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Comment by Trek1701on Jun 02, 2022 11:08am
142 Views
Post# 34726536

RE:RE:The Big IF

RE:RE:The Big IF

Either you must be new here or you don't know this company very well. They have been supposedly trying to partner one or more of their programs for over a decade. They had a (poor) deal at one point for ALS with Biogen that fizzled out when. This was under the previous CEO.

Going back to at least 2018, the company repeatedly noted potential deals with multiple possible companies, which all went nowhere. You might want to review corporate presentations from that time where they threw around numbers such as $50 million upfront and $600 million in milestone payments.

Your idea is good (and rather obvious to everyone); the problem is that current management can't get it done.

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