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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Post by MrMugsyon Jun 03, 2022 3:38pm
213 Views
Post# 34730598

Bristol ...

Bristol ...BMS is in a tough spot - as with a few other Big Pharmas and their patent cliff situation out to 2030.
There will be lots of desire to acquire or partner with good companies over the next few years.

For example ... if we just look at BMS, they have three drugs coming off patent

Revlimid (2026), Eliquis (2029) - partnered with Pfizer ... and ... Opdivo (2028).
Revenues totaling  $28.3B/year (including Pfizer's portion of Eliquis).

We seem to be on the right side of needed acquisitions to shore up revenue losses from patent expirations and if we prove ourselves ... there will be gold at the end of the rainbow.

That's why a successful acute run is important - why a chronic solution (during P2 Acute) is important and 352/IBD can also help set the stage for the big dance.

If anyone thinks we've lost value by not going to P3 with a 7 year chronic drug ... let's see what you think when they pull 20 year protections in various respects.  That's my sprots bet.
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