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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a development stage biotechnology company. The Company is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), an alpha-synucleinopathy. Its proprietary target discovery engine applies a thermodynamic, computational discovery platform - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product portfolio includes PMN310 / Amyloid-beta, PMN267 / TDP-43, and PMN442 / Alpha-synuclein. The Company plans to investigate additional synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Its wholly owned subsidiary is ProMIS Neurosciences (US) Inc.


NDAQ:PMN - Post by User

Comment by M101on Jun 22, 2022 2:07am
108 Views
Post# 34773044

RE:RE:RE:RE:acu193 question

RE:RE:RE:RE:acu193 question
Was there a mention of Acumen in a prior corporate update? I know ACU193 appears in a paper by Cashman & Plotkin, but it wouldn't fit well in a table comparing P2-3 drugs to demonstrate the need for oligomer selectivity, it needs to fail first.

I like the direction of evololution of this document.
I'd like to see a summary of P1 level competion framed in the context of next generation drugs in developement, and ACU193 would certainly fit there. I think that can be done without casting shade and doing so would help potential investors' DD, as well as demonstrating managerial confidence and competence. Seems like a no brainer when the facts are on your side. 
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