RE:Safety and Partial Response Kingpin68 wrote:
Perhaps others can clarify something. Keytruda states almost 19% had an 'ongoing' response at 12 months. I was trying to find if that was CR only or included PR. TLT has significant PR as well and I wonder if PR patients would be saved from having bladder removal. If so, this is significant data. I also knew from this board that the view was that tld1433 was much safer than keytruda but didn't realize the scope of safety concerns with keytruda. Their site talks about keytruda causing the immune system to attack normal organs and tissue, which can happen even after treatment and possibly lead to death. Not sure how prevalent that issue is, as I couldn't find more specific info. It seems so far that TLT's treatment is far less risky.
Good points King. The thing qith 1433, as you've alluded to at least. PRs are important. Cuz with low adverse reactions, high safety. 1433 can be re-tried. Over and over, turning NRs to PR/CRs, turning PRs to CRs... ;-)