Theratechnologies Inc T.TH

Alternate Symbol(s): THTX

Healthcare Biotechnology

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. It blocks viral entry into host cells while preserving normal immunologic function. The Company is also investigating an intramuscular method of administration of Trogarzo. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy.

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Theratechnologies Inc > Now this could be interesting!

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Comment by jeffm34on Jul 09, 2022 3:44pm

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Post# 34813097

RE:Now this could be interesting!

https://www.nature.com/articles/s41587-020-00791-6

Trogarzo is mentioned in this article as an antiviral mAb that has been approved but not as a mAb being looked at for treatment of coronaviruses

"The use of antibodies as antivirals is gaining momentum. In the 20 years after Synagis (palivizumab) was approved for use against respiratory syncytial virus (RSV), no other mAbs targeting viral pathogens were registered. In 2018, Roche/Genentech received a green light for Trogarzo (ibalizumab) for the treatment of multidrug-resistant HIV; and early last year, the Food and Drug Administration approved Regeneron’s Inmazeb antibody cocktail treatment for Ebola"

SPCEO1 wrote: Saw this on Twitter:

Nicole Saphier, MD

@NBSaphierMD

A few antivirals available by prescription when given early that can help prevent/lessen viral illness: Valtrex, Tamiflu,Trogarzo,Lagevrio. Yet, the FDA is allowing Paxlovid, one of the least studied antivirals, be given without an Rx. Pfizer must have a friend at the FDA.

8:51 PM · Jul 8, 2022 Twitter for iPhone