RE:RE:RE:RE:RE:RE:QuestionsFrom what I have seen is that we have POC for TH1901. I spoke with Christian a few times in the last couple of years. I asked him, we believe TH1902 can overcome MDR1 but what about the other resistance mechanism? He told me that they didn't know. Now that you have POC of TH1901 you can move on to more toxic bombs that you know will overcome the other resistance mechanisms. In my opinion, this should set up a deal with big pharma or with the Chinese.
qwerty22 wrote: I think the 53% PR is POC practically and scientifically. It's never 100% but it's hard to ascribe a solid response like that to anything other than the drug. There is some free docetaxel floating around which could account for it. Maybe that could be the cause but Christain did say that patient failed docetaxel treatment recently after 4 cycles. I think what we can see is they are always ultra cautious in their statements.
SPCEO1 wrote: From a practical perspective, we have POC and indications the drug works. from a scientific perspective, neither has yet been achieved. So the scientists are not going to be satisfied until it is, as they should not be. But we can take away from today's news that we will likely get the scientific proof needed before too much longer.
Bucknelly21 wrote: Kinda find some on this board funny, been waiting for poc and an efficacy signal, we get it finally and its not good enough lol