RE:RE:RE:RE:RE:20% of all Global Deaths ?Hey SM,
Long time follower of this board and investor. The EUPHRATES trial ( for which the current confirmatory TIGRIS trial is based) was the first randomized, controlled and blinded study for the treatment of endotoxic septic shock. Studies up to this point were smaller and not as robust. That is why this current open label, bayesian confirmatory trial which builds on EUPHRATES is such a big deal.
See the link for a great article by Claudio Ronco
https://ccforum.biomedcentral.com/articles/10.1186/cc13912
PM