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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Comment by MrMugsyon Aug 07, 2022 9:43am
258 Views
Post# 34877014

RE:RE:RE:RE:antiviral ...

RE:RE:RE:RE:antiviral ...
Jefnan1 wrote: Any time line for acute news?


It's hard to tell.
It seems there's lots of science on-the-go right now.
Don't have the details - just know they are busy.

Updates are lagging and it seems for good reason - won't know until the give us information.

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For Example ...

Expecting the commercial study for OTENA-acute and that might be a September thing.

By my calculations, I see a $7.2-$9.6 BB peak sales year (out in 2041) and that's if you assume 15-20% market share.  Seems kind of low if you are planning for a best-in-class product - but - that alone would be double chronic's peak year sales expectations (due to longer IP coverage).

In reality - what percentage should we get with a safer and non-addictive post-op med?
Is 30% more realistic?
Then we'd be looking at peak sales > $14 BB at peak annual sales.

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Also waiting for a 352 update but I think we're waiting even longer for that now.  Likely a Q4 update when we get the IBD update.

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Not sure if there's much of an update coming with the Q1 numbers - not sure what they could discuss unless they can give us a progress report on some of the science that's underway and the plans for Fast-Track/Breakthrough Therapy.

There is no doubt we are heading down the FDA fast-track program route but we need details to really understand.




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