Oncolytic virus combined with immunotherapy in glioblastomaAugust 08, 2022 - " Recently, several treatment strategies known as immunotherapies including CAR T cell therapy, dendritic cell vaccines, immune checkpoints blockade and oncolytic virus, nano particles and gene editing/silencing technology have demonstrated promising results in preclinical and few clinical trials.
Furthermore, to increase the efficacy of these novel strategies, combinatorial approaches are being implemented for the treatment. This includes CAR T cell therapy in combination with small molecules, immune checkpoint inhibitors and oncolytic virus and nanoparticles plus gene editing, silencing or immune checkpoints inhibitors.
These treatments have shown exciting results in preclinical settings and few of these trials are in progress."
https://www.tandfonline.com/doi/abs/10.1080/08830185.2022.2101647?src=&journalCode=iiri20