Join today and have your say! It’s FREE!

Become a member today, It's free!

We will not release or resell your information to third parties without your permission.
Please Try Again
{{ error }}
By providing my email, I consent to receiving investment related electronic messages from Stockhouse.

or

Sign In

Please Try Again
{{ error }}
Password Hint : {{passwordHint}}
Forgot Password?

or

Please Try Again {{ error }}

Send my password

SUCCESS
An email was sent with password retrieval instructions. Please go to the link in the email message to retrieve your password.

Become a member today, It's free!

We will not release or resell your information to third parties without your permission.
Quote  |  Bullboard  |  News  |  Opinion  |  Profile  |  Peers  |  Filings  |  Financials  |  Options  |  Price History  |  Ratios  |  Ownership  |  Insiders  |  Valuation

Theralase Technologies Inc. V.TLT

Alternate Symbol(s):  TLTFF

Theralase Technologies Inc. is a Canada-based clinical-stage pharmaceutical company. The Company is engaged in the research and development of light activated compounds and their associated drug formulations. The Company operates through two divisions: Anti-Cancer Therapy (ACT) and Cool Laser Therapy (CLT). The Anti-Cancer Therapy division develops patented, and patent pending drugs, called Photo Dynamic Compounds (PDCs) and activates them with patent pending laser technology to destroy specifically targeted cancers, bacteria and viruses. The CLT division is responsible for the Company’s medical laser business. The Cool Laser Therapy division designs, develops, manufactures and markets super-pulsed laser technology indicated for the healing of chronic knee pain. The technology has been used off-label for healing numerous nerve, muscle and joint conditions. The Company develops products both internally and using the assistance of specialist external resources.


TSXV:TLT - Post by User

Post by thadeushon Aug 12, 2022 7:38pm
312 Views
Post# 34893216

Vaccine for Lyme Final Trial

Vaccine for Lyme Final Trial
A vaccine for Lyme disease is in its final clinical trial August 9, 202212:25 PM ET BILL CHAPPELL A vaccine candidate for Lyme disease is moving through the clinical pipeline, as the tick-borne disease spreads to new areas. Here, a tick is seen at the French National Institute of Agricultural Research. Bertrand Guay/AFP via Getty Images Ticks that carry Lyme disease have been on the march, spreading into more forests and brush areas around the U.S. and Europe. But lovers of the outdoors could get a new weapon against Lyme, if a new vaccine candidate performs well. It aims to protect people as young as five. If it were to gain regulators' approval, it would become the only Lyme disease vaccine available for humans in the U.S. But it's expected to take years for the potential vaccine to reach the market. If the phase-three study is a success, the companies say, they would likely seek official authorization in 2025. Forbidding Forecast For Lyme Disease In The Northeast The new vaccine is called VLA15, and as of this week, it's now in the third phase of a clinical study in humans. It was created by Pfizer and French drugmaker Valneva. "We are extremely pleased to reach this important milestone in the development of VLA15," Valneva's chief medical officer, Juan Carlos Jaramillo, said in a statement. "Lyme disease continues to spread, representing a high unmet medical need that impacts the lives of many in the Northern Hemisphere." U.S. consumers once had access to a human Lyme disease vaccine, called LYMERix, but it was withdrawn from the market 20 years ago. The vaccine had fairly high efficacy, but some users blamed it for adverse reactions, including arthritis. As the National Institute of Allergy and Infectious Diseases notes, "analysis by the FDA and others did not support that conclusion" but use of the vaccine plummeted, leading to it being discontinued. There is, however, a vaccine on the U.S market for dogs. The new human vaccine candidate works in a way that's similar to LYMERix, targeting an outer surface protein of the Borrelia bacteria that cause Lyme disease. But VLA15 omits a protein region "that some had attributed to adverse events," according to the NIAID. The study that's now underway includes some 6,000 participants in the U.S. and Europe who are at least 5 years old and who live in places where Lyme disease is "highly endemic," Pfizer and Valneva say. The vaccine candidate provoked a strong immune response in adults and kids in earlier trials, "with acceptable safety and tolerability profiles," according to the drug companies. Aside from the potential vaccine, another weapon against Lyme is also in the works: a monoclonal antibody developed by MassBiologics, which is part of the University of Massachusetts Medical School. The first phase of human trials for the antibody is expected to conclude this month, with a second phase likely starting next spring. Lyme disease is spread by black-legged ticks. Climate change and deforestation are among the human-caused factors that have increased the range of the arachnids. The removal of predators that control populations of deer and mice, two animals that carry Lyme, also has helped the disease spread. People face a greater risk of Lyme disease if a tick remains on their skin for a prolonged period, leading experts to urge people to check themselves for ticks after spending time outside, particularly in areas where Lyme is known to be a threat. Early Lyme symptoms can include a fever, headache and a circular rash that can resemble a bull's-eye, according to the CDC. Later symptoms can include joint pain, facial palsy and inflammation of the brain and spinal cord. The disease can be treated with antibiotics, especially in its early stages. Some people have been known to develop persistent symptoms, such as pain, fatigue and an inability to focus. 2022 npr https://www.npr.org/2022/08/09/1116500921/lyme-disease-vaccine-final-clinical-trial-phase
<< Previous
Bullboard Posts
Next >>