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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Aug 19, 2022 10:44am
133 Views
Post# 34907301

RE:RE:RE:RE:BMS acquires Turning Point's TKI platform for USD$ 4.8 Bln

RE:RE:RE:RE:BMS acquires Turning Point's TKI platform for USD$ 4.8 BlnPfizer's tyrosine kinase inhibitor (TKI) is sunitinib malate (Sutent) and we know that coadministration of the TKI sunitinib with reovirus could further reduce tumor burden resulting in improved survival, decreased accumulation of immune suppressor cells, and the establishment of protective immunity upon tumor rechallenge.

https://www.pfizer.com/products/product-detail/sutent

[ And as stated beforehand, an I/O combination of ONCY's pelareorep + immune checkpoint inhibitor (ICI) + a tyrosine kinase inhibitor (TKI) could become an effective triplet in the treatment of solid tumors, such as kidney and GI cancers. ]
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