"Sepsis is a life-threatening complication caused by a dysregulated host response to infection. Sepsis and septic shock remain major healthcare problems. In 2017, there were 48.9 million incident cases of sepsis and 11.0 million sepsis-related deaths worldwide, representing 19.7% of all global deaths"

https://janesthanalgcritcare.biomedcentral.com/articles/10.1186/s44158-022-00056-5