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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Post by themagicboxon Aug 26, 2022 5:06pm
193 Views
Post# 34923624

"Tylenol most dangerous drug ever made?"

"Tylenol most dangerous drug ever made?"Just to augment my point on tyelonl from a previous post:

https://www.acsh.org/news/2017/09/11/tylenol-far-most-dangerous-drug-ever-made-11711

and shows just how skewed the risk vs theraupetic effect (therapeutic index) is for tylenol. And compare that to what on the market, then compare it to the available data on ATB-346/Otenaproxesul.  

Tylenol (acetaminophen) an analgesic (pain reliever) gets a free pass in the minds of many people because it doesn't come with the liabilities of the NSAIDs, such as aspirin and ibuprofen - bleeding, heartburn, kidney toxicity, ulcers, and salicylate allergy. The absence of gastrointestinal toxicity is responsible for the widespread perception that Tylenol is safer. In some ways it is, but in others, it is not. It may leave your stomach alone, but not your liver. 
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