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Algernon Pharmaceuticals Inc. C.AGN

Alternate Symbol(s):  AGNPF

Algernon Pharmaceuticals Inc. is a clinical-stage drug development company. The Company is focused on developing repurposed therapeutic drugs in the areas of non-alcoholic steatohepatitis (NASH), a type of liver disease, chronic kidney disease (CKD), inflammatory bowel disease (IBD), idiopathic pulmonary fibrosis (IPF) and chronic cough as well as advancing a stroke program using N, N-Dimethyltryptamine (DMT). The Company operates through two segments, which includes the development of repurposed therapeutic drugs in Canada and the facilitation of the Company’s lead drug candidates into off-label phase II clinical trials (humans) in Australia. The Company's pipeline includes NP-251 (Repirinast) and AP-188 (DMT). The Company, through its subsidiary, Algernon NeuroScience Inc., is developing AP-188 (DMT) as a potential treatment for stroke and traumatic brain injury (TBI) recovery. Its NP-251 is being developed as a potential treatment for kidney inflammation and fibrosis.


CSE:AGN - Post by User

Post by StockHawk1on Sep 12, 2022 4:48pm
131 Views
Post# 34957807

Breakdown for AGN's latest clinical study approval

Breakdown for AGN's latest clinical study approval

Today Algernon Pharmaceuticals Inc. (AGN.c AGNPF) announced that it has received approval to conduct a Phase 1 clinical study of an IVF of DMT for the treatment of stroke. AGN plans to dose the first subject of the study in Q4.


AGN decided to investigate DMT for ischemic stroke because multiple independent preclinical studies demonstrated that DMT helps mitigate tissue damage and promotes neurogenesis & neural plasticity. 


AGN also found that DMT increased the growth of cortical neurons by up to 40% compared to control in its own pre-clinical study.


The first part of the clinical IVF study will try to identify a safe non-psychedelic dose.


The second part will test the effects of repeated administrations of the non-psychedelic dose. 


More info here:

https://ca.finance.yahoo.com/news/algernon-pharmaceuticals-receives-approval-groundbreaking-110000273.html


AGN @ $6.01

MC $11.924M

 
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