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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Comment by Trek1701on Sep 17, 2022 12:27am
138 Views
Post# 34968653

RE:Drinking the wrong Koolaid with Phase 1

RE:Drinking the wrong Koolaid with Phase 1

You must be new here. Biogen's market cap increased by about $40 billion after encouraging results from phase 1 for BIIB037 in 2015. That trial measured benefits (cognition) as well as safety. Might have been a phase 1b but definitely not a phase 2 or 3. I think at least a few would describe a $40 billion market cap increase as "exploded". All it takes is a couple of minutes to look up some information. You can try it yourself:

Expectations had been high ever since a Biogen executive told investors at a bank conference in Boston last December that aducanumab was showing a dose-dependent benefit on both amyloid removal and cognition.

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