RE:RE:RE:RE:RE:RE:ONCY pelareorep + CAR-T therapy as explained by Mayo ClinicShould read ... Combining the 3 complementary therapies could prove to be highly synergistic, since ONCY has already demonstrated synergy in combination with CAR-T and Immunune checkpoint inhibition, .... and the addition of ONCY's pelareorep to the above stategies is proving to be an effective means to increase CAR-T persistence and durability, reverse an immunosuppressive tumor microenvironment (TME) for a more effective immune checkpoint inhibitor therapy, and is demonstrating the ability to overcome both antigen escape and resistance induced by T-cell immunotherapy and checkpoint blockade, respectively, in the treatment of solid tumors.
Therefore a triple combination therapy of CAR-T, immune checkpoint inhibition, plus ONCY's pelareorep could become a highly effective therapy for the treatment of various liquid and solid cancers.