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Claritas Pharmaceuticals Inc V.CLAS.H

Alternate Symbol(s):  CLAZF

Claritas Pharmaceuticals, Inc., formerly Kalytera Therapeutics Inc, is a biotechnology company that is focused on developing R-107 for the treatment of vaccine-resistant coronavirus disease (COVID) strains. The Company’s products in development include R-107 for coronavirus disease and Viral Infections, R-107 and Vaccines, and CLA-1816 for treatment of pain. R-107 is designed to defeat COVID viruses on contact. R-107 targets the Achilles heel of COVID, the spike protein on the surface of the virus. R-107 releases nitric oxide, which attaches to a specific amino acid on the spike protein, thereby disabling the spike protein. The CLA-1816 provides effective pain reduction, without the risks of addiction or respiratory suppression that exist with opioid analgesics. CLA-1816 strongly binds with and activates the alpha3 glycine pain receptor in the spine. The Company has leased a laboratory, office, and archival space in Beverly, Massachusetts.


TSXV:CLAS.H - Post by User

Post by Red~Oneon Sep 20, 2022 10:53pm
232 Views
Post# 34975419

Nitric Oxide: The Missing Factor in COVID-19 Severity?

Nitric Oxide: The Missing Factor in COVID-19 Severity?"What started as an observation of the correlation between the severity of COVID-19 symptoms associated with old age, and the age-related decline of NO levels, has now tied low NO levels to all major high-risk groups of COVID-19 infection. This overwhelming amount of correlation data and the sound biochemical reasoning behind low NO levels and the corresponding conditions that increase COVID-19 infection severity as well as the symptomatology exclusive to COVID-19, the successful utilization of NO gas as a therapeutic option, and the emergence of evidence tying NOx to COVID-19 severity, make further research on the matter warranted."

3.2. Nitric Oxide and COVID-19 Patient Outcomes: What Does the Evidence Suggest?

"Since the conception of the authors’ hypothesis that COVID-19 severity and pathology is correlated to NO bioavailability and successful treatment and prevention options can be developed manipulating this pathway, clinical evidence supporting this hypothesis has emerged. "


LINKhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788438/
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