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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Post by Mole101on Sep 27, 2022 8:03pm
177 Views
Post# 34990869

Alzheimer’s Progression Slowed by Drug in Major Trial

Alzheimer’s Progression Slowed by Drug in Major Trial

https://apple.news/Ak4Xc5nA5ThyiEY6_S-bP4w
 

Eisai Co. and partner Biogen Inc. said their Alzheimer’s drug lecanemab slowed the disease, becoming the first medicine to clearly blunt the progression of the most common type of dementia in a final-phase trial. 

The drug slowed cognitive decline in people with early Alzheimer’s by 27% over 18 months when compared with a placebo using a common rating scale, meeting the main goal of the trial, according to a statement from the companies on Tuesday. While modest in size, the effect was highly statistically significant. ..

 

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