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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by jfm1330on Sep 29, 2022 8:39pm
81 Views
Post# 34996458

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:Montreal's Ventus Therapeutics

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:Montreal's Ventus TherapeuticsIt seems oral peptide is inching closer to reality with insulin.

https://www.biopharma-reporter.com/Article/2022/05/05/Oramed-hits-oral-insulin-clinical-trial-milestone


Wino115 wrote: At this point, NASH is not a "value-accelerator" for us as shareholders. I've sort of assumed that if they can get oncology into a "highly probable" commercial trajectory (meaning good Phase 2 on at least 1 cancer type), they may contemplate investing $20-30mil into moving NASH finally into it's Phase 2b on their own over a 24 month period.

Strategically, if you are looking at the potentail for a revenue line of $200mil + in 24 months, it might be a worthwhile investment to take a bit to push along the NASH program. If we all get lucky and it's something like HR+, TNBC, Ovarian, Lung, Melanoma, or one of the big ones with a $500mil+ revenue line, then it's definitely worth pushing it along. They own it, the clinical data was intriguing and the market is huge.  The large market size, even for 3rd, 4th, or  5th entrants, will still be large. Especially for something that is very safe. But as we sit here, it's all about oncology to create shareholder value. 

On making it a pill, long ago the scientists on this board said it was not possible. 

PWIB123 wrote: We don't have a pill.  That is all. What would prevent us from making a pill?

Bucknelly21 wrote:

i think its a reasonable assumption that nash is fading away, maybe im wrong i hope i am but they dont talk much about it and the fact that they said they were in a strong position to negotiate i feel is a bit of a stretch, i have no data to support the comparison beside mdgl basically using a similar method as thtx and mdgl seems to be the front runner for first nash approval. 

 

palinc2000 wrote:

 

I did not attempt to do a comparative analysis of the Nash data between the THTX  and Ventus..
Can you share  your findings?

 

Bucknelly21 wrote:

 

that's assuming you take paul for his word, not so sure i really do. If you have a company down the road with far less data safety ect sign a partnership you either arent having those talks or  its just not a thing. And they need to stop acting as if they are trying. 

 

palinc2000 wrote:
Financial markets  in research targeting Nash including merger and acquisition potential  are  in revival mode in the last few weeks/months ....and the last Corporate Presentation mentions ''Actively pursuing discussions with companies that have interest ,capabilities and resources''

 

 

qwerty22 wrote:

Maybe "Not right now thanks" rather than never. But I think you've mostly got your expectations set right.

 

longterm56 wrote: If there is not enough interest in Egrifta for NASH to generate a partnership, do you really want THTX to go it alone? I'm sure big pharma has looked at it and has said, "no thanks". So why would they pursue it?

 

Lee430 wrote: If we did not have this potential high reward cancer platform would Thera have kept their eyes on the NASH prize and it would maybe be in PH3 by now instead of sending it to the time out chair?


Biobob wrote: I understand the frustration since I share it on a daily basis since 1998.  I wprobably wont happen but we can hope a business update on October 13 delivers soemthing that makes Paul seemingly more verbal about Th1902...

 

 

 

 

 

 

 

 




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