RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:Designing the basket trialsYou never know what's going to happen. Who tought Egrifta would be approved after the panel meeting back in 2010... nobody i can tell you. I saw massive insider purchases and overly optimistic behavior from CEO's just before complete implosion of many former biotech darlings. I saw insiders sell their holdings in companies just before takovers and lose millions in the process after accumulating and holding on to their shares for decades. So nobody know if tomorrow we will have a POC, a Takover, A nash partner.... I know at least they got some drugs approved in 2010 and 2018 and that the CEO did'nt work at MacDonalds before he joined the company.