RE:"importance of macrophages in finding new treatments"There's the good and bad side of macrophages. Y-BG is showing potential to reduce the inflammatory response and the cytokine storm and this could be due to it's abilitiy to re-program the macrophages. Preventing, stopping, (and maybe even reversing early stage) fibrosis and inflammation (ongoing for long Covid patients) is what the CZO/McMaster research is all about. It's taking more time that most of us would have hoped, but solid pre-clinical studies are needed before moving to human trials.
Getting Y-BG as an immune booster to market, or as an eventual inhalable prophylatic / therapeutic needs to be accelerated given the worldwide health crisis.