Important article in 25th October Nature
https://www.nature.com/articles/d41586-022-03392-2 ------------------------------- I know from many articles that Pelareorep activates RAS pathway and is Cytotoxic to some forms of KRAS. But it looks like its becoming more important and focused on recently. -------------------------------------------------- " and can be found in nearly every type of tumour. Such mutations are particularly prevalent in some of the deadliest cancers: more than 80% of pancreatic cancers carry a KRAS mutation, for example, as do roughly 30% of lung adenocarcinomas and colorectal tumours." ---------------------------------------------------------- Cheers!!!!!