RE:RE:RE:EY sees bolt-ons in the single to double digit billions now Bolt-on acquisitions in the single to double digits Billions falls within the US$5 to 15 Billion "sweet-spot" that PwC global consultants have forecasted given the US$1.7 Trillion in firepower that Big Pharma has at its disposal for M&A deals to be undertaken to offset the looming patent cliff that Big Pharma is facing by 2025.