RE:Excellent Interview with Matt Coffey - June 2021Proboscises posted this note below on Nov 11.
I went to spotify and found it and listened through. This is the most revealing and remarkable interview or news piece I have ever encountered about ONCY. It clearly explains the twists and turns in the thinking, science context, and assorted trials and why the seem to all have surprising results. First they were surprisingly bad, compared to what they thought would happen. After they began to appreciate ONCY as an I/O agent and not a lytic agent, they started getting results that were surprisingly good. After listening to this whole interview, which was conducted in 2021, I now finally have a much better understanding of the twists and turns to get to where we are now.
I also can see that pure luck has played an enormous role here this process, as well as the evolution of I/O understanding the role of folks like Richard Vile.
I also realize the role of dumb luck that got me into what should have been a failed biotech that is now on the verge of greatness. The strategy they started with would have died if not for scientific and pharmacological changes in the world, and thus their fortunate guidance from the FDA, input from Vile etc. .
Again, no one can deny the power of our recent results.