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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Comment by jfm1330on Nov 16, 2022 9:41pm
148 Views
Post# 35105475

RE:RE:RE:RE:RE:RE:Soleus influence?

RE:RE:RE:RE:RE:RE:Soleus influence?I got my 8th treatement with Lu-177-Dotatate today. Two hours of road in a snowstorm to come back home after treatment, several cars and big trucks were off the road on the highway. It was very dangerous and long (twice the normal driving time)

That being said, I am in a clinical trial even if Lutathera is approved in Canada. It's a trial for personalized dosing of Lu177-Dotatate and for treatment beyond the initial four treatments. Luthatera is approved for only the initial four treatments. They cannot give it beyond that. So what I get is not the commercial Lutathera, it's the same molecule, but not the commercial one. FDA wants a separate study on retreatments before approving it, even though it clearly works in Europe and it works for me.

But I wrote just to say that in my case I will need to go back three days after treatment for a scan, this scan will show the effect of my treatment from August, but other than that, they gave me the request for blood tests to be made at 2, 4 and 6 weeks post treatment, and I just need to go to a small hospital near my home to get it done, since we have a universal healthcare system here in Quebec, results will be transfered to the doctors in Quebec City, and to my oncologist in Sherbrooke. They are all on the same informatic platform. So no need to make long trips only for blood tests.




juniper88 wrote: Rather than enrollment, I would be more worried about retention.  The TH-1902 trial does weekly blood test for no good reason that I can see.  They are just the rudimentary blood test CBC, liver function, etc.  I have not seen this done by any other phase I trial.  Usually they just do it same day as the next infusion.  When you are desperate to be on a trial you think to yourself that you can handle it.  But these are people that have already gone through a long cancer journey.  They are tired and the weekly blood test becomes very tiring very quickly.  Someone who has stable disease for a few months is going to ask is it worth living this way.  My wife asked me "How long will I have to keep doing this?" People just want to be able to live a normal life and to that end the difference between having to come in once every 3 weeks or once a week is huge.



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