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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Nov 19, 2022 4:17pm
243 Views
Post# 35112985

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:Tactics used x Hedge Fund & MM to acquire shareholder stock

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:Tactics used x Hedge Fund & MM to acquire shareholder stockwestcoast1000 - I think you summerized the past and now the present quite well. In the past 10 years ONCY has taken pelareorep through proof-of-concept, Phase 1 safety and efficacy trials, and now Phase 2 clinical trials in multiple cancers that are demonstrating efficacy and that pelareorep is a platform technology which can be used with various immunotherapies such as immune checkpoint inhibitors, CAR-T, bispecifics, and small molecule immuno-oncology agents.

As a result, Big Pharma has become most certainly aware of pelareorep's "bolt-on" acquisition potential since such a deal would help fend-off the looming patent-cliff challenge that Big Pharma is facing by 2025.

Bringing ONCY's pelareorep into Big Pharma's oncology franchise sooner than later would give the acquirer of ONCY a shortened timeframe to gain FDA/EMA marketing approval (i.e. accelerated approval) for pelareorep in combination with their IO agents and a shortened timeframe to run a post approval confirmatory trial (which ONCY is currently describing as a Phase 3 trial but can be better viewed as a post approval confirmatory trial). However the process, it would be ONCY's Big Pharma acquirer to decide on how they want to position pelareorep for both condicitonal and final regulatory approval, should they choose this pathway among several..   
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