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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Healthcare Biotechnology
Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Oncolytics Biotech Inc > Advanced Pancreatic Cancer Trial - NU 18I01
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Comment by Noteableon Nov 22, 2022 7:45pm
143 Views
Post# 35120379

RE:Advanced Pancreatic Cancer Trial - NU 18I01

RE:Advanced Pancreatic Cancer Trial - NU 18I01 ONCY decided to go with the Goblet-1 pancreatic cancer study instead since it was a multi-centered study with a significantly reputable German clinical reserach group known as AOI. The pancreatic study included the biomarker work and was successfully reported on at the KOL meeting held on November 14, 2022.  The following pancreatic cancer results were achieved:

One complete response (CR) and eight partial responses (PR) achieved in thirteen evaluable patients

69% objective response rate (ORR) is nearly three times greater than the average ORR of ~25% reported in historical control trials

Data support Oncolytics' plan to advance its pancreatic cancer program into a pivotal study

Data to be discussed during a key opinion leader webinar on November 14th at 10 a.m. ET


https://www.oncolyticsbiotech.com/press-releases/detail/586/oncolytics-biotech-presents-updated-clinical-data-at-sitc
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