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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Post by SABBOBCATon Dec 01, 2022 11:27pm
346 Views
Post# 35145284

Fool me 4 times shame on you... this is the 5th...

Fool me 4 times shame on you... this is the 5th...I hear the optimism from some folks that this is merely a pivot on the learning path, but what I don't think is resonating with me until now is the repeated failures of this organization. They are becoming too many and too loud to ignore. 

  1. Commercialization of Egrifta: This is an old old story some may or may not know
  2. Re-commercialization of Egrifta: This is the more recent story we have seen slowly play out with lackluster results
  3. Commercialization of Trogarzo: Never achieved a significant fraction of the projected market share, with delayed launch of IVPush/IM formula, and the abandonment of the european market. 
  4. Phase 2/3 NASH: the "position of strength" appears to be balled up in the corner doing SFA. No material progression in years. 
  5. TH1902: P1A delayed as they didnt want to admit to a lower dose so they scraped into 1B and realized that they now need to reconfigure again. so another 6-8 months of delays on top of the initial 6-8 months. 

Absent of a favorable partnership announcement in NASH or oncology, I don't see any near term upside that would prevent another OO. Yet management deemed a 6:30PM press release sufficient to communicate to investors how screwed they are with no planned call for further clarity? How disrespectful and out of touch are these folks? 

The only thing I can think of is their hand was forced somehow in communicating this. Was it the Cantor report that eluded to it that made them realize they inadvertently let it slip? or is there some other deal that is pending that requires the disclosure? Time will tell. 

SPCEO, I can only imagine the conversations you now have to have with your clients and I would not be surprised if this was the straw (or hay bale) that broke the camel's back, but if you do stay, I think you finally agree that something needs to be done about the culture and direction. 

Absense of big news or big change, I may need to finally say enough is enough and move on. It is going to be a tough puill to swallow as I broke every rule on this one and will take a long time to come back from this, but I cant ignore the greener pastures any longer. 

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