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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Post by Joemareon Dec 05, 2022 2:31pm
281 Views
Post# 35151612

45-60 days prior to strategy update

45-60 days prior to strategy updateI believe it's the minimum time before FDA comes back with a final decision regarding TH's proposal changes. I doubt we will get anything prior to that.   This PAUSE is a little worrisome as efficacy was the issue for the pause. Ex. If efficacy was an issue for 7/8 indications assess, the PR would have been much different and efficacy for the '8th' indication would have been detailed. I think they can't ascertain proof of concept yet + efficacy (partial/complete/stable response) is likely less than 20%.  

That sucks.  I can tell you that no one was blinede to the trial data. They knew back in the summer they had issues and response rate sucked.  I think heads should soon roll.
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