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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Dec 14, 2022 11:31am
165 Views
Post# 35170953

RE:RE:RE:RE:Merck & Moderna combine Keytruda + personalized mRNA vaccine

RE:RE:RE:RE:Merck & Moderna combine Keytruda + personalized mRNA vaccineIn the Phase IIb KEYNOTE-942 trial, patients treated with Moderna's mRNA-4157/V940 vaccine plus Merck’s Keytruda (pembrolizumab) saw a 44% reduction in the risk of recurrence or death, as compared to those given Keytruda alone. This effect proved to be statistically significant, with a p-value of 0.0266. 

Based on these data, the powerhouse partners plan to engage regulatory authorities in preparation for a Phase III study, set to launch next year

As the demand for coronavirus vaccines wanes, Moderna is seeking
 to expand its mRNA technology into other therapeutic areas, ensuring its success remains sustainable. It would be reasonable to think that Pfizer is also facing the slow-down in 
coronavirus vaccines and is therefore intending to bolster it's current pipeline through "bolt-on" acquisitions.  
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