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biOasis Technologies Ord Shs V.BTI.H

Alternate Symbol(s):  BIOAF

Bioasis Technologies Inc. is a Canada-based biopharmaceutical company focused on research and development of technologies and products intended for the treatment of patients with nervous system, including central nervous system, diseases and disorders. The Company is engaged in the development of its xB 3 platform, which is a peptide-based technology, for the transport of therapeutic agents, in particular biological products, across the blood-brain barrier (BBB). It is focused on both orphan drug indications, including brain cancers, and rare genetic neurodegenerative diseases and neuroinflammatory conditions. The Company is also focused on its Epidermal Growth Factor (EGF) platform for treating rare and orphan neurodegenerative and neuroinflammatory disorders. EGF is a protein that stimulates cell growth and differentiation, notably for myelin producing cells. Its development programs include xB3-001: Brain Metastases, xB3-002: Glioblastoma and xB3-007: Neurodegenerative Disease.


TSXV:BTI.H - Post by User

Post by prophetoffactzon Dec 19, 2022 10:29am
188 Views
Post# 35179490

MTX110

MTX110 BTI's bold move places an important bet on Midatech's lead clinical asset MTX110. If this drug works Biodexa becomes a much stronger company, potentially. The lead trial with MTX110 is for an ultra-rare pediatric cancer.

Looks like some clinical data within about one month:


"In addition, the company expects to report data in the next couple of months from the second Phase I study assessing MTX110 in DIPG, conducted by Columbia University." Edison Group November 15
Midatech Pharma - Patient recruitment begins in rGBM study | Edison (edisongroup.com)

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"As a reminder, Midatech had earlier (in October 2020) presented interim data from its other UCSF conducted Phase I study, which not only met its primary endpoint in terms of safety but also demonstrated exceptionally positive early efficacy signals, including median overall survival of 26.06 months (CI 11.3–26.06 months) versus 10 months following standard of care radiation therapy." Midatech Pharma - Interim DIPG data to be presented at ISPNO | Edison (edisongroup.com)


A
nother clinical trial using MTX110 just enrolled its first patient recently and targets glioblastoma which is a $5 billion market. The trial for the ultra-rare pediatric cancer using the same drug and delivery technology would appear to support the glioblastoma trial.
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