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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Dec 27, 2022 5:51pm
141 Views
Post# 35192859

RE:RE:RE:RE:Where we are now as ONCY shareholders

RE:RE:RE:RE:Where we are now as ONCY shareholdersWrong on thinking about the use of pelareorep as a "salvage" therapy since in pancreatic cancer for example thete is no real effective therapy,  however pelareorep + immune checkpoint inhibitor was able to be an effective therapy, leading to a "cure" in 1 patient and partial responses in most of the rest studied.

Then there is the use of pelareorep + immune checkpoint inhibitors in the treatment of early breadt cancer.

However why you may think of pelareorep as a salvage therapy is because the FDA requires that an emerging new cancer therapy demonstrates safety and that usually happens in late stage patients. Now that has been accomplished there is little for ONCY's acquirer to stop using pelareorep in earlier disease patients.
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