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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Healthcare Biotechnology
Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Oncolytics Biotech Inc > Moderna's CEO Stephan Bancel comments on mRNA cancer vaccine
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Comment by Noteableon Jan 09, 2023 6:27pm
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Post# 35212261

RE:RE:RE:Moderna's CEO Stephan Bancel comments on mRNA cancer vaccine

RE:RE:RE:Moderna's CEO Stephan Bancel comments on mRNA cancer vaccineThe ability of ONCY's oncolytic virus pelareorep to be delivered intravenously (IV) contributes to pelareorep's affect in remodeling the TME since the virus is widely dispersed throughout the body and not essentially localized to one area as happens when a drug is delivered intratumorally (IT) or subcutaneously. Any potential absocopal effect through IT delivery is not systemic, and fails in poorly immunogenic tumors (i.e. cold tumors)  
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