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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Comment by MrMugsyon Jan 18, 2023 10:09am
340 Views
Post# 35230394

RE:RE:Quiet day ...

RE:RE:Quiet day ...The next earnings report (late Feb ???) should indicate that cash was around $42.5 MM for the last quarter.  That includes initial payment for the CITA sale.

As we understand it - the IBD candidate should have been selected and I can only assume we are waiting for the IP to be accepted at the patent office before they talk about it. 

I'm looking for a few things w.r.t. the IBD drug ... that being ... how deep a solution it is ...
     - Crohn's ???
     - Colitis ???
     - IBS ???
This will depend on the mechanisms employed ... H2S release, even release throughout the intestines (large and/or small), iron scavenging and any other mechanisms they may employ.

Solving the entire gut seems to be the key to all other problems - so - we need to get 346 and IBD right.

In terms of the share price ... nothing is more important than a perfect run at OTENA-acute (346).  This is the catalyst that we need more than anything.  So, we wait for GMP pills and we wait for PK Study in order to refine the Phase 2-Acute study.  Also, these events are what opens the door to OTENA-chronic (determining if once a day at lower dose works - OR - if we need to look at sophisitcated regimen control to deal with the liver's personality).

Leave no money on the table (w.r.t. OTENA).
That's how I look at the events of 2023 unfolding.
All about mining the full value of this drug.

Good Luck !
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