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StageZero Life Sciences Ltd T.SZLS

Alternate Symbol(s):  SZLSF

StageZero Life Sciences, Ltd. is a Canada-based vertically integrated healthcare company. The Company is engaged in improving the early detection and management of cancer and other chronic diseases through diagnostics and telehealth programs that provide clinical interventions to assist patients who have cancer (COC Protocol), and help patients reduce the risk of developing late-stage disease (AVRT). Its test, Aristotle, is the first mRNA multi-cancer panel for simultaneously screening for multiple cancers from a single sample of blood with high sensitivity and specificity for each cancer. Aristotle uses mRNA technology to identify the molecular signatures of multiple cancer types and is built on the Company's patented technology platform, the Sentinel Principle. The Care Oncology Clinic offers a supervised treatment regimen (the COC Protocol) for people diagnosed with cancer of any type or stage. Its ColonSentry is a proprietary blood test for screening for Colorectal Cancer.


TSX:SZLS - Post by User

Post by LithLoveron Feb 15, 2023 1:06pm
256 Views
Post# 35287794

New Care Oncology study results and new website coming

New Care Oncology study results and new website coming

The METRICS study was conducted by the London, UKCare Oncology Clinic between 2013 - 2016 using a perspective analysis comprising 95 patients with a biopsy confirmed Glioblastoma IV brain tumor ("GBM"). Patients could be enrolled into the adjunctive COC Protocol at any time i.e., from presentation of their GBM or at any future time-point if deemed eligible to receive treatment by the consulting COC oncologist. All patients continued to receive their standard of care therapy (surgery, radiation, chemotherapy) and follow up.


The primary endpoint was median overall survival (defined as time from diagnosis until death from any cause):



  • Patients receiving the adjunctive COC Protocol had a median overall survival of 26.3 months and a two-year survival of 55.8%.

  • Comparative data from Public Health England (Brodbelt et al., 2015), patients receiving standard of care therapy alone had a median overall survival of 14.8 months and a two-year survival of 28.7%; and data from the European Organisation for Research and Treatment of Cancer, a median overall survival of 15.8 months and a two-year survival of 26.5% (Stupp et al., 2005).
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