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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Feb 26, 2023 10:53am
150 Views
Post# 35305756

RE:Genentech exploring mRNA vaccine for Pancreatic Cancer

RE:Genentech exploring mRNA vaccine for Pancreatic Cancer In 2016 Genentech agreed to pay BioNTech $310 million in upfront and “near-term” payments in a collaboration that was aimed at developing mRNA vaccines to treat multiple cancer types. The companies also agreed to share equally all development costs and any potential profits for certain programs.

In June 2016 , Merck & Co. and Moderna Therapeutics launched a $200 million partnership
 in a scramble to develop mRNA-based personalized cancer immunotherapies.


https://www.genengnews.com/topics/omics/genentech-biontech-to-partner-on-mrna-cancer-vaccines/

Since ONCY never entered into an upfront payment with any Big Pharma partner, ONCY's fair value is well in excess of UD$8 Billion on the strength of ONCY's shareholders having carryied all the costs associated with ONCY's clinical trial program in various cancers. Having ONCY shareholders carry the entire costs either happened by plan or happenstance but eitherway ONCY's value is not tied to any particular company's upfront payment, so the acquiition value of pelareorep and the company is now before any Big Pharma company who will make the highest acceptable offer - which now is estimated in excess of US$8 Billion - at a time when Big Pharma is faced with a looming patent cliff that can only be addressed through M&A and the 'bolt-on' acquistion of external assets  that complement the acquirer's product pipeline, as ONCY's pelareorep is capable of accomplishing.
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