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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Mar 25, 2023 1:49pm
175 Views
Post# 35360407

RE:RE:RE:RE:RE:RE:RE:RE:FDA guides on how AA can be converted to full approval.

RE:RE:RE:RE:RE:RE:RE:RE:FDA guides on how AA can be converted to full approval.In 2022, pre-Phase 3 targets made up 50% of M&A deal volume for the very first time as Big Pharma companies  are increasingly moving toward earlier-stage assets to gain access to innovative and novel drug therapies in light of Big Pharma's looming patent cliff. With Pfizer's proposed take-over of  Seagen for US$43 Billion, Big Pharma leaders are acknowledging that they must pay a premium for de-risked acquisitions in oncology which represents the highest ROI.

Over the years ONCY has conducted multiple clinical trials on its immune molecule platform technology pelareorep that has resulted in the de-risking of pelareorep in multiple cancer indications and which now comes at a premium to its Big Pharma acquistion partner.

In analyzing the success of M&A transactions, global life science consulting companies like EY have found
 that bolt-on transactions yield better results for the acquiring Big Pharma companies when the target company is in a therapeutic area adjacent to the core portfolio of the acquiring company, as ONCY has positioned itself as a M&A target. Consultants like EY further suggest that target companies see more success if they build depth and expertise in specific therapeutic areas, which ONCY has achieved, rather than diversifying across a broad range.

Consequently ONCY's acquistion value for its synergistic I/O biologic platform technology that can enhance the effectiveness of PD-(L)1 immune checkpoint inhibitors straight-forwardly falls within Big Pharma's M&A "sweet spot" range of US$5 to $15 Billion.

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