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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Mar 26, 2023 5:22pm
211 Views
Post# 35361450

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:FDA guides on how AA can be converted to full approval.

RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:FDA guides on how AA can be converted to full approval.Reportedly the cost for a course of intravenous checkpoint inhibitor therapy is around $US150,000 to $250,000 while the rate of effectiveness is between 10 - 20 %.

With ONCY's pelareoep continuing to prove synergistic effectiveness in combination with PD-(L)1 immune checkpoint inhibitors, the increased degree of efficacy would result in an increased number of patients who could be placed on 
PD-(L)1 immune checkpoint inhibitor therapy, and this increase in patient numbers could result in an overall decrease of checkpoint inhibitor cost, thus making it more accessible to more patients.

The plausible ability to reduce the cost of 
PD-(L)1 immune checkpoint inhibitors when combined with pelareorep, would seem to make the acquisition of ONCY an attractive proposition for Big Pharma companies with ICIs.

https://www.globenewswire.com/news-release/2023/02/13/2607142/0/en/Checkpoint-Inhibitors-Global-Market-Report-2023.html
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