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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to registration-enabling clinical studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Mar 27, 2023 7:03pm
160 Views
Post# 35363506

RE:Pfizer turns over Bravencio to Merck.

RE:Pfizer turns over Bravencio to Merck. Along with Pfizer wanting to avoid potential antitrust issues on the acquisition of Seagen, by divesting in Bavencio (avelumab),  Pfizer is developing its own PD-1 immune checkpoint inhibitor - sasanlimab, which can be administered subqutaneously (subQ). Roche's (atezolizumab)Tecentriq  and Merck's (pembrolizumab) Keytruda have also developed their own subQ immune checkpoint inhbitors.

So still Merck, Roche and Pfizer, notwithstanding today's development. Pfizer, Merck and Roche's antibody drug conjugates (ADC) are all able to benefit from the addition of ONCY's pelareorep in combination with immune checkpoint inhibitors. 
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