Looking for a new director On March 29, 2023, Richard Gregory, a member of the Board of Directors (the "Board") of ProMIS Neurosciences Inc. (the "Company"), notified the Company of his intent to not stand for re-election to the Board at the Company's 2023 Annual Meeting of Stockholders (the "Annual Meeting") and, as a result, his term as a director of the Company, or on any committee of the Board, will end upon the conclusion of the Annual Meeting. Mr. Gregory's decision to resign from the Board did not result from any disagreement with the Company on any matters relating to the Company's operations, policies or practices. The Company extends its deepest gratitude to Mr. Gregory for his distinguished service to the Board and lasting contributions to the Company.