RE:RE:RE:RE:RE:AACR - late breaking absracts text posted by noon todayIs this contradictory as it increased the Tumor growth? Would you not have expecedt the TH1902/anti-PD-L1 combination to reduce Tumor growth better than TH1902 alone? So how does the mouse live longer then?
In a first study, the TH1902/anti-PD-L1 combination resulted in increased tumor growth inhibition when compared with both agents alone. Interestingly, TH1902 as a single agent showed better tumor growth inhibition than docetaxel or docetaxel/anti-PD-L1 combination. In a second study, the TH1902/anti-PD-L1 combination significantly increased animal survival over either anti-PD-L1 or TH1902 as single agents (21 days increased median survival compared to 2.5 and 12.5 days respectively).