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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Healthcare Biotechnology
Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Oncolytics Biotech Inc > Merck USA (MSD) acquires Phase 2 biotech for US$ 10.8 Bln.
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Comment by Noteableon Apr 16, 2023 2:03pm
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Post# 35397444

RE:RE:RE:RE:Merck USA (MSD) acquires Phase 2 biotech for US$ 10.8 Bln.

RE:RE:RE:RE:Merck USA (MSD) acquires Phase 2 biotech for US$ 10.8 Bln.Another good and demonstrated example is ONCY's pelareorep affect on the tumor microenvironment (TME) in which ONCY has shown that pelareorep is able to convert a hypoxic and immunosuppressive TME into one that is conducive to the addition of PD-1 checkpoint inhibition. 

Pelareorep is able to turn "cold" tumors into a "hot" tumor, and in so doing is able to stimulate the innate and adaptive immune system, in the right patient, at the right time, and by doing so is able to overcome the problem of T-cell exhaustion.

And like some recent acquisitions of next generation biotech assets that Big Pharma companies are making, ONCY provides a powerful precision medicine platform with pelareorep that leverages this proprietary technology to translate complex and deep patient data into precision therapeutic and predictive/prognostic diagnostic product candidates, designed to provide effective treatment solutions for patients with immune-mediated diseases, involving "precision medicine" and cancer.
 
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