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Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Post by westcoast1000on Apr 26, 2023 3:15pm
221 Views
Post# 35415334

Who and what

Who and whatThe talk is being given by Amy Clark of U Penn. She is likely the PI or senior trial coordinator for this trial.

She is Deputy director of clinical trials and an Assistant Prof in U penn medical school and hospitals.

Note the title of the talk:

BRACELET-1 (PrE0113): Inducing an inflammatory phenotype in metastatic HR+/HER2- breast cancer with the oncolytic reovirus pelareorep in combination with paclitaxel and avelumab.

I would not be surprised if this talk focused on what is mentioned in the first part of the title: inducing an inflamed phenotype. Maybe she will not be reviewing the deeper reults of the trial in terms of outcome measures. Those might wait, or be addressed separately.


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