RE:RE:RE:RE:So they STILL have not applied for BTD???
Clarification of previous post highlighted below...
My focus is on the Swimmer's plot...it tells a very interesting story, particularly at the 180 & 270 day marks.
For those patients who maintained a CR throughout the first 270 days & who have also been assessed at 360+ days (total of 11 patients), 9 of 11 (82%) maintained a CR at 360+ days. The remaining 2 are IR, which would give a total response of 100% for this subgroup. There are 2 other patients who have also maintained a CR throughout the first 270 days who have yet to be assessed at 360 days. Based on the above trend, there's a good chance those 2 will also be CR at 360 days, or at least IR. Imo, there's a good chance that of the 27 who have reached the 270 day or longer mark, we could have at least 11 of the 27 (41%) maintain their CR at 450 days.
Of the 15 patients who maintained a CR through 180 days, 13 of 15 (87%) maintained a response at 270+ days, 11 of those 15 (73%) were CR, & only 2 of 15 (13%) were NR for that subgroup.
According to the Swimmer's plot, data seem to be trending swimmingly. The plot clearly demonstrates that optimization is working & if a patient can remain CR for 270 days, there's a good chance he/she can save a bladder. All imo.
Additionally, if you dismiss the first 12 undertreated in Study II, our 90 day CR would increase from 54% to 63%. Looking at the 180 day assessment mark, our CR would increase from 62% to 80%.
Keep the data coming : )