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Oncolytics Biotech Inc ONCY


Primary Symbol: T.ONC

Oncolytics Biotech Inc. is a biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and adaptive immune responses to treat a variety of cancers. This improves the ability of the immune system to fight cancer, making tumors more susceptible to a broad range of oncology treatments. The Company’s primary focus is to advance its programs in hormone receptor-positive / human epidermal growth factor 2- negative (HR+/HER2-) metastatic breast cancer and advanced/metastatic pancreatic ductal adenocarcinoma to phase 3 licensure-enabling studies. In addition, it is exploring opportunities for registrational programs in other gastrointestinal cancers through its GOBLET platform study.


TSX:ONC - Post by User

Comment by Noteableon Apr 30, 2023 2:26pm
155 Views
Post# 35421731

RE:RE:RE:Merck USA (MSD) acquires Phase 2 biotech for US$ 10.8 Bln.

RE:RE:RE:Merck USA (MSD) acquires Phase 2 biotech for US$ 10.8 Bln.Forget about the old thinking that one Phase 3 indication is worth just US$1 Billion, given the dramatically changing M&A landscape driven by the looming patent cliff and the push for novel biologics by both industry and government, a per the IRA.

Recent examples of M&A deals included pre-clinical companies like Trillium Therapeutics acqured by Pfizer for US$2.3 Billion; late-stage Phase 2 companies like Prometheus Biosciences being acquired by Merck for US$10.8 Billion; and Horizon Therapeutics acquired by Amgen for US$27.8 Billion, without ever licensing a drug on its own, just as several examples.

Recently GSK paid $2 Billion for Bellus Health, a single indication cough company.

ONCY has a platform technology that can be used in multiple cancers and multiple indications, with multiple I/O agents including PD-(L)1 immune checkpoint inhibitors, CAR-T therapy, bispecifics and antibody drug conjugates (ADC), and small molecules therapie like PARP and CDK 4/6 inhibitors.

Furthermore a US$10 Billion valuation for ONCY comfortably falls within Big Pharma's M&A 'sweet-spot' of between US$5 and US$15 billion for bolt-on assests like ONCY's platform technology pelareorep that would not be subject to an FTC review thus leading to a quick close for multiple Big Pharma companies looking to bolster their drug pipelines.


https://fortune.com/2023/04/13/horizon-therapeutics-drug-marketing-amgen-acquisition/


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