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biOasis Technologies Ord Shs V.BTI.H

Alternate Symbol(s):  BIOAF

Bioasis Technologies Inc. is a Canada-based biopharmaceutical company focused on research and development of technologies and products intended for the treatment of patients with nervous system, including central nervous system, diseases and disorders. The Company is engaged in the development of its xB 3 platform, which is a peptide-based technology, for the transport of therapeutic agents, in particular biological products, across the blood-brain barrier (BBB). It is focused on both orphan drug indications, including brain cancers, and rare genetic neurodegenerative diseases and neuroinflammatory conditions. The Company is also focused on its Epidermal Growth Factor (EGF) platform for treating rare and orphan neurodegenerative and neuroinflammatory disorders. EGF is a protein that stimulates cell growth and differentiation, notably for myelin producing cells. Its development programs include xB3-001: Brain Metastases, xB3-002: Glioblastoma and xB3-007: Neurodegenerative Disease.


TSXV:BTI.H - Post by User

Comment by prophetoffactzon May 12, 2023 11:37am
305 Views
Post# 35445504

RE:RE:Zacks on PLX:

RE:RE:Zacks on PLX:
unclepieman wrote: and what if ANYTHING will do for BTI?


You tell us.

Chiesi identified Lysosomal Storage Disorders as a strategic area for growth. Its billion dollar licensing deal with Protalix for Fabry is Chiesi's flagship strategic asset in Lysosomal Storage. Chiesi also has other minor interests in Lysosomal Storage. Fabry has now been approved in Europe and the US. It is game on. The enzyme could benefit from delivery to the brain given the nature of Fabry and may be part of Chiesi's xB3 deal.

Given Chiesi's strategic interest in Lysosomal Storage and now that it has an important position and that the race to treat the brain is also on for Lysosomal Storage as evidenced by DNLI, etc., is it now full speed ahead when it comes to Chiesi's xB3 license? Chiesi has licensed 4 xB3 Lysosomal Storage opportunities. Given Chiesi's postion in the sector and that BTI kept other Lysosomal Storage opportunities(eg. Hunter, Gaucher's) in its own pipeline will there be a second xB3 deal with Chiesi? Could BTI sell its pipeline of xB3 opportunities to Chiesi for upfront cash and sell the remaining value of the Chiesi deal(outside of XOMA) back to Chiesi to clear its debt and move forward? Could BTI and Protalix merge and enter a second deal with Chiesi for xB3? Protalix also has a Gaucher's Lysosomal Storage enzyme. Gaucher's is in BTI's current pipeline. 

 
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